Dreaming Despite Despair

Dreaming

and reasoning, is capable of suggesting, if not establishing, far-reaching laws of cerebral activity, inasmuch as the brain energies revealed by consciousness, and sometimes attested by objective manifestations, occur while the organ is out of relation with any impressions derived from the outer world, and is left, so to write, to its spontaneous and uncontrolled motions. Dreaming has been attr...

Fisheries: hope or despair?

Recent work suggesting that fisheries depletions have turned the corner is misplaced because analysis was based largely on fisheries from better-managed developed-world fisheries. Some indicators of status show improvements in the minority of fisheries subjected to formal assessment. Other indicators, such as trophic level and catch time series, have been controversial. Nevertheless, several de...

Despair on disparities.

In this issue of Annals of the Rheumatic Diseases, Sokka et al (see page 1666), by analysing the data from the Quantitative Standard Monitoring of Rheumatoid Arthritis (QUEST-RA) cohort, with over 6000 patients from 25 countries, warn us of possible disparities in the health of patients with rheumatoid arthritis. This international team of researchers found a clear association between gross dom...

Despair and Hope

Genome Dreaming

We investigate and build the framework required to generate or “dream” of genomes that encode novel organisms. Importantly, we find that developing methods to validate the generated sequences is as important as building a good model to realize this task due to the lack of methods capable of interpreting and evaluating a generated sequence. We report on our results in building and optimizing a g...